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EP245: Cancer in anus | PUTTING DR G ON THE SPOT
The Star
Follow
10/27/2024
Consultant urologist Dr George Lee Eng Geap, or a.k.a Dr G, enlightens on the risks and danger of anal warts developing into anal cancer.
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Transcript
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00:00
Hello there, welcome to the last installation of putting Dr. Chee on the spot in the month
00:04
of October when we're focusing a lot of issues related to HPV.
00:09
We've dealt with genital warts, cervical cancer and oropharyngeal cancer and today we're going
00:14
to deal with anal cancer.
00:22
Anal cancer is well known to be associated with HPV.
00:26
In fact there are two types of HPV, one is HPV-16 and HPV-18.
00:32
What is believed is that although somebody can actually get rid of the disease itself
00:36
with a natural immunity, however some people may not be able to get rid of it and that
00:42
will turn into genital warts and subsequently will cause changes in the cells and the early
00:49
pre-cancerous changes may lead to cancers of the anus.
00:54
So many people don't know that HPV in fact affects women a lot more than men, especially
01:00
older women.
01:01
We actually don't know why.
01:03
However we know that older women who are age 60 and above are more subjected to HPV infection
01:10
in the anus and subsequently may progress to anal cancer.
01:16
So contrary to common belief that anal cancer only happens in men having sex with men, in
01:23
fact the chances of men getting such cancer is about three-fold less than a woman.
01:29
So what exactly is causing anal cancer?
01:33
The HPV transmissions during sexual activity or during contact may actually harbour itself
01:40
on the anal verge and then with the lower immune system or somebody who actually have
01:47
higher prognostic risk factors such as smoking, the cells may change form and turn into cancerous form.
01:56
In fact it's observed in most high-income nations that anal cancer is creeping up by
02:02
about 2% in women and 2.6% in men over the last decade.
02:08
So therefore it is important for men, especially men, to actually build their immunity through vaccination.
02:16
We know that the chances of men developing natural immunity from HPV 16 and 18 is as
02:23
low as 3-8%.
02:26
Therefore with a bit of helping hand from the vaccination, their immunity can go up
02:31
to as high as 97% of antibody being produced after exposure to the vaccine within 7 months
02:40
and the antibodies is sustained for more than 90% over a 10-year period.
02:46
And if the study shows that, then we know nature is given a bit of a helping hand to
02:51
boost men's response to contracting HPV and that subsequently will reduce the risk of
02:59
getting anal cancer, oropharyngeal cancer, genital wart and also renal cancer in men.
03:06
For following week, if we are venturing into the month of November and Movember, November
03:12
we also focus on another form of cancer which is predominantly male-related cancer.
03:19
So next week we're going to talk about the diagnosis of prostate cancer and how do you
03:23
know you've got prostate cancer.
03:26
So if you're interested, stay tuned for next week's Putting Dr. G on the Spot.
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