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Retirement news: Highly-regarded doctor on Alzheimer's warning signs
The Street
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5/24/2025
Dr. Manisha Parulakar of Hackensack University Medical Center shares how to know when you need to get checked.
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Sports
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00:00
this morning on brn signs it's time to take your memory loss seriously and joining me now to
00:11
discuss this and a lot more dr manisha parulakar of hackensack university medical center dr parulakar
00:18
great to see you thanks for joining us in the program this morning thank you for inviting me
00:23
yeah it's great we're talking about memory and i guess my first question is how do you figure out
00:31
whether or not forgetfulness needs to be taken more serious and that it could lead to
00:39
a potential alzheimer's or dementia diagnosis
00:42
before i used to jokingly tell my patients that if you forget what you forgot we have a problem
00:52
and we need to we need to get a formal assessment and formal evaluation
00:58
the topic has changed a little bit more now especially because we do have the new treatment
01:05
options available which are for patients with mild cognitive impairment so not necessarily the
01:12
diagnosis the pre pre-dementia stage of mild cognitive impairment and what that looks like is
01:20
if you are having difficulty doing your day-to-day task something that you've been doing for years
01:27
and had no problems but now all of a sudden you need a much longer time to complete that task maybe
01:34
that's paying the bills managing your calendar managing a project if you are having a harder time and
01:42
you're requiring much longer time and many more resources to finish it maybe there is something going
01:48
on and you should talk to your doctor about it and and and so that takes some personal awareness
01:55
but what about um a family member i mean is this something that a family member could check
02:01
with their loved one uh you know to see if hey you know they're just not completing the tasks
02:07
the way they used to complete the task but but and also doctor um you know we we slow down a little
02:14
bit as we age i know i'm a lot slower than i was in my 20s absolutely and those are those are two
02:20
important points and one is that some slowing down does happen to all of us that's the loss of brain
02:26
plasticity and all of us are going to have that as we age being said that it still should not interfere
02:33
with our activities that we were doing so well so we should still be able to pay our bills the same
02:39
way that we were doing 10 years ago i may have a difficult time figuring out setting up a new
02:45
process so if i was setting up a new account to do that that may take a little bit longer but if i was
02:53
doing something like handwriting my checkbook i should be able to do that in a timely manner so if i'm
02:58
taking much longer and if i'm asking many more questions and that's something the family members can
03:03
observe is that if the loved one are they asking a lot of questions for their usual activity
03:09
are they not able to do the cooking that they were doing without going back to the the recipe
03:15
or asking questions about recipe are they just repeating questions that they're forgetting the
03:21
conversation that they had uh not that long ago so those are all warning signs that okay there's
03:27
something going on so so doctor if you if you see something going on what's the first and you're a loved
03:33
one let's just say uh or an individual you you feel something's not right what's the first step you
03:40
should take should you call your internist your general practitioner or do you go directly to
03:45
someone like yourself who's a specialist in cognitive functions and alzheimer's and dementia
03:50
i would say it depends on what access you have so if you do have access to a memory center around you
03:58
reaching out to them and making an appointment is a great idea because they have all the resources and
04:04
and they can really especially when it comes to mild cognitive impairment which is a very
04:08
um it's a diagnosis it's a accurate diagnosis it does require a lot of multiple steps to get there
04:14
so if you have access that would be great but unfortunately we don't have those many memory centers around
04:21
so talking to your primary care physician is a great first step and they could start with some
04:28
of the basic testing and then decide whether further investigation is needed yeah and and then they would
04:35
refer to you to someone like yourself or or someone else to help address and and see what the root
04:43
cause of it of it could be uh doctor you mentioned as we age you know the brain is not as elastic i
04:51
think is the term you use but are there are there things that we can do to create better elasticity
04:59
and improve the longevity of our of our thoughts of our brains of our memories absolutely and i think
05:07
that's the reason why it is so crucial for us to start thinking about our brain in our 40s and 50s
05:13
and not because we definitely know that alzheimer's is a very long process it's about it's going on for
05:20
about 10 15 years before it starts producing those memory symptoms so it really is important for all
05:27
of us to to work on the plasticity and to maintain our function of the brain and the big threats for
05:34
our brain health are our chronic conditions so managing your high blood pressure managing your
05:40
diabetes managing your cholesterol are really essential to maintain that brain health the second
05:46
big threat is our mobility so not moving enough is is an important risk factor so just having any
05:55
mobility is better than none but continuing to move and newer data suggesting that we want to be
06:01
mobile throughout the day so not just hitting the gym for one hour but then saying sedentary of the
06:07
rest of the day that doesn't help either so staying active and not not sitting at one place for too long
06:13
is helpful managing our sleep which is something else that we don't necessarily pay attention to a lot
06:19
of people will walk around saying oh i do fine with four hours of sleep we know that's the time that our
06:26
brain spends in in managing our deep memories creating new memories so we need to have that says six to
06:34
seven hours of sleep ideally seven to eight hours of sleep to be able to recharge the brain for the next day
06:41
um and then of course staying away from substances um we are finding more and more evidence that
06:48
alcohol is really not good for us even small amounts of smoking some other substance use like
06:54
marijuana they all have negative effects on your brain so staying away from substance use is another
06:59
great way to um to maintain your brain health um and managing a lot of times the substance use is
07:04
related to uh behavioral health issues so managing the behavioral health issues by getting the right help
07:10
um meditation yoga are great ways to to help almost all behavioral health issues as a basic step
07:18
so addressing all of them uh together or we can technically push um the risk of dementia to a much
07:26
much later part of our life and last question for you doctor in terms of treatment are are we further
07:33
long in terms of the research and medications that maybe can delay or even reverse some of the effects
07:41
of these of this disease so a lot of yes we do have new medications especially for alzheimer's or
07:50
mainly for alzheimer's that can be used in that mild cognitive stage of the disease or very early
07:55
dementia disease um and it can it does have potential of progress slowing down the progression to some
08:02
extent we don't have anything right now that actually reverses the disease so we're still working on that
08:09
and a lot of studies are showing that the non-pharmacological interventions that we just talked about
08:15
the exercise the sleep the brain exercises um can be equally helpful in slowing down the progression
08:24
and sometimes even maybe reverse it especially if you're in the mild cognitive phase and if you
08:28
address all of those um that can be potentially helpful yeah i mean and alzheimer's it sounds like
08:36
doctor alzheimer's if you take the right steps alzheimer's doesn't have to be the end result of aging
08:41
it doesn't have to be the the thing that ultimately we all get absolutely and and there are people
08:50
telling us that that's true if you look at the blue zone um where people are living to be 100 and a lot
08:58
of them have their their memory intact um so that that tells you that following those non-pharmacological
09:05
interventions socializing um and having that support structure can protect our brain health and
09:12
potentially help us prevent or at least push it to a much much later time part of our life
09:17
well doctor you you talked about treatment i want to ask you about maybe the uh ask you about the
09:23
blood test where we look at biomarkers how successful is that blood trust and should i go
09:29
run out to the store and take it or to the doctor and take it and get it okay so um yes to first question
09:37
no to second question so yes we have done a significant progress in in helping in building biomarkers
09:43
um in alzheimer's and now we're using similar knowledge to look at louis body and other types
09:48
of dementias as well um so we have much more we have gotten much more sophisticated to have that
09:53
accurate diagnosis and yes we have moved from doing the cerebral spinal fluid to now blood to able to
10:00
help us with those uh with the accurate diagnosis uh but those blood tests should be ordered in the
10:07
context of um if somebody has memory issues has had some invested some workup and there is a
10:15
possible diagnosis of alzheimer's so it's not a screening test we should not be just going and
10:21
getting it um and we should not definitely be asking our doctors to say that hey you're doing
10:26
my blood work can you add that screening test for alzheimer's as well yeah it's not going to be
10:30
showing up on the on the lab core menu anytime soon i guess but it is it is it is on the it is on
10:36
the lab core and quest menu and that's the reason i'm making a point even further that please don't
10:41
ask for it just because it's on the menu yeah very very smart well doctor thank you so much again for
10:46
joining us and we look forward to having you back on the program again very soon thank you so much
10:51
and don't forget to subscribe to our daily newsletter the morning pulse for all the news in one place
10:56
details of course at our website and your subscription supports all this great brn content including
11:02
the show you were just watching and we're back again tomorrow for another edition of brn until
11:08
that i'm jeff snyder stay safe keep on saving and don't forget roll with the changes
11:12
you
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