Shares in Asia-Pacific slipped in Friday trade, with Japanese markets among the region’s biggest losers. In Friday afternoon trade, the Nikkei 225 fell 2.31% while the Topix index shed 2.16%. For the week, the Nikkei lost 4.89%, the biggest loss since the market crashed after the coronavirus outbreak in early 2020. Mounting fears that supply chain disruptions worldwide could keep inflation elevated for a much longer period contributed to the sentiment. Also weighing on investor mood was a delay in a vote on the Biden Administration’s spending bills. With price pressure rising globally due to staff shortages, lack of ships, soaring gas prices in Europe and power shortages in China, investors are starting to fear inflation is not temporary.