Study Identifies Genes That May Lead to Autism

A study led by researchers from the Medical University of South Carolina identified genetic alterations that may be responsible for the development of autism. Scientists have identified the MEF2C gene, which is involved in muscle development as one one of the potential culprits. The gene is highly expressed in the brain, and has been previously associated with severe neurodevelopmental disorder and intellectual disabilities. MEF2C is one of many genes implicated in development of autism. However, investigators believe this particular gene has a profound effect on the expression of many other genes. Cowan says his findings support the theory that autism results from impaired synapse connections formed between brain cells.