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  • 16/07/2025
Um novo estudo da Universidade do Texas em El Paso revela que o consumo de álcool afeta a tomada de decisões de forma diferente entre os sexos, impactando mais os machos. A pesquisa com roedores mostrou que ratos machos alteraram drasticamente suas escolhas sob influência do álcool, enquanto fêmeas mantiveram suas decisões originais. Essas descobertas sugerem uma vulnerabilidade de gênero aos efeitos do álcool, com implicações para a compreensão do comportamento humano.

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Transcrição
00:00Alcohol impacts decision-making more in men than in women, study says
00:05CNN Brazil.
00:07It is widely recognized in the scientific community that alcohol consumption impacts decision making.
00:12of decisions.
00:13However, a recent study suggests a variation in this influence between the sexes,
00:18with the effect most pronounced in males.
00:21The research, conducted by scientists at the University of Texas at Opazo, UTEP, was published in the
00:28earlier this month in Alcohol and Alcohololiz magazine.
00:31The study employed an animal model, using rodents to investigate the different effects
00:36of alcohol consumption in males and females during a decision-making task.
00:41It was observed that male rats under the influence of alcohol significantly altered their
00:46decisions, demonstrating a preference for higher concentrations of the substance.
00:51In contrast, female rats maintained their original decisions, formulated in a state
00:56of sobriety.
00:57Our findings demonstrate that acute alcohol consumption profoundly affects decision making.
01:02decision-making processes of male rats, suggesting a gender-specific vulnerability to
01:07effects of alcohol, said Alexander Friedman, assistant professor in the Department of Science
01:13Biological.
01:14He adds that this study is particularly relevant because it contributes to the understanding
01:19the neural foundations of decision-making and how the alcohol-induced state can influence
01:26our choices.
01:28To carry out the research, scientists used the REVAR-COSH system in the socket
01:33of decisions in rodents, RECOD.
01:35They developed a specific arena to assess the rats' propensity to approach or avoid
01:40solutions with different concentrations of sucrose and alcohol, simulating mixed drinks
01:46and sweetened alcohol often consumed by humans.
01:49Initially, the rodents were exposed to the arena without the presence of alcohol, receiving
01:54just sweetened solutions at varying levels.
01:57The team recorded the decisions and preferences demonstrated by the rats in their sober state.
02:03With the introduction of alcohol into the diet, it was found that male rats changed considerably
02:08your preference.
02:09Opting for solutions with higher concentrations of alcohol, differing from their
02:14initial predilection for sweeter solutions in a sober state.
02:18Some of these changes in decision-making in male rats persisted for up to
02:23two months after exposure, indicating possible long-term cognitive effects.
02:28In contrast, female rats, despite consuming proportionally more alcohol
02:33in relation to their body weight, they have largely maintained their original weight patterns.
02:39decision making, established when surs.
02:43The researchers highlight that the results of the study transcend the experimental environment,
02:48offering insights into how acute alcohol intake may influence alcohol intake
02:53of risk decisions and behaviors differently between the sexes in humans.
02:57This understanding is crucial, considering that moderate alcohol consumption constitutes
03:02a common part of everyday life.
03:04This work has the potential to support more targeted approaches to dealing with
03:10substance use and its consequences, and exemplifies the kind of significant science
03:16and translational work we seek to support, said Robert Kirkin, dean of the College of Sciences
03:21of the PICU.

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