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  • 2 days ago
Fertility expert Dr Natasha Ain Mohd Nor breaks down the difference between Intrauterine Insemination (IUI) and In Vitro Fertilisation (IVF) - two of the most common fertility treatments today.

Whether you're just starting your fertility journey or exploring your options after trying naturally, this episode offers clear, honest answers to help you make the best decision for your future family.

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YOUTUBE:
https://www.youtube.com/watch?v=m7OWratEjv8&t=2693s

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Transcript
00:00Some of the myths, if they do IVF, it's 100%. It's not, right?
00:04So age then comes into the medicine.
00:07Sometimes you go, doctor's trying to push me for IVF.
00:09No, we're looking at your age, right?
00:10We know this is the things that we experience statistically
00:14and also on a day-to-day basis.
00:16We do struggle when the wife's age is much more older.
00:22So maybe you could break down the difference between IUI,
00:25intra-retrine insemination, and also in vitro fertilisation.
00:28I mean, just by the name, of course, you know the difference between those two.
00:33But which group of patients maybe they can try with IUI, some of them with IVF?
00:39And what would be the success rate between these two?
00:42Right, so IUI basically stands for intra-retrine insemination
00:45and IVF is in vitro fertilisation.
00:48So the fertilisation occurs outside for IVF
00:52and the fertilisation occurs inside for IUI.
00:55So IUI is super simple.
00:56Basically, we will put the female partner or the wife on some medications,
01:03fertility tablets, just to make the eggs a little bit, one or two, enough.
01:07And then we'll then monitor the follicles.
01:09And once it gets to a certain size where the eggs is mature,
01:12and usually this falls any time between day 11 to day 15 of the cycle,
01:16which is ready for the process.
01:19And we give one injection to basically make the egg ovulate or rupture
01:23and it's fertile time.
01:26And the husband on that day would then come to the lab or the fertility centre
01:31or bring it from home.
01:33And we'll just inseminate a processed sperm,
01:36which means we basically take the best swimming sperm or the fastest moving sperm
01:41so that we get the best pregnancy rate inside the uterus.
01:44Now, how we put it, it's just a very small, fine plastic catheter,
01:48put it through the vagina, through the cervix,
01:52feels like a pap smear or less painful.
01:55Okay.
01:56So it's really super simple.
01:57Then you will wait for two weeks whether your period comes or not.
02:00If your period does not come, possibility you may be pregnant.
02:03And we have like, you know, very simple tablets after the IUI.
02:07Super simple.
02:08You can continue your activity as usual.
02:12Pregnancy rate, unfortunately, is about 10 to 15% for each cycle for the younger ones.
02:17Costs may be roughly about 2,000 to 3,000,
02:19depending on how much hormones you're using and which setting you are doing.
02:24Now, for IVF, it's different.
02:25It's much more strenuous.
02:27You're going to start on your second day or third day of your period.
02:29Depends on the protocol, but majority of the time,
02:32second day or third day of your period,
02:35and then you'll be injected.
02:37Okay?
02:37Injected daily.
02:39I'm sure you've been through it, right?
02:41The majority will be injected daily for at least a good 10 to 12 days
02:45with scanning maybe two to three times in between.
02:48And on the day, usually again, mid-cycle,
02:50anytime between day 12 to day 16 of the period,
02:54you will be ready for an egg pickup.
02:56It's all done as a daycare procedure.
02:58Procedure, nothing at the tummy.
03:00You will be asleep, right?
03:02A light sleep.
03:02So you won't have any pain.
03:04And you'll be then, the needle will go through your vagina,
03:07nothing through the tummy.
03:08You're asleep.
03:09Half an hour procedure, you go home at lunchtime, most of the time.
03:12So no need to stay overnight in hospital.
03:15Then we do the fertilization in the embryo,
03:17the embryologies in the IVF lab.
03:19And usually we'll wait at least five to seven days
03:22to see how many total of fertilized egg or what we call embryo
03:26that we are able to vitrify or what we're able to freeze and utilize.
03:32Right?
03:32So then, after that, usually it's going to be either a fresh or frozen embryo transfer.
03:37Now, fresh means any time between three days or five days after the egg pickup,
03:42you will have a transfer.
03:44Procedure, similar like an IUI, similar like a PAPS immunosomal disease.
03:48Super simple, no sedation.
03:50You'll be fine.
03:50Right?
03:51You don't need the sedation.
03:53Right?
03:53And then, after that, you will wait and you'll be giving some medication.
03:57Some is oral form, some are vaginal suppository, some may require injections.
04:02Okay?
04:03So you will then do that for maybe 10 to 12 days.
04:06Do a urine pregnancy test or a blood test.
04:08Okay?
04:09So then you will know whether you have conceived or you have not conceived.
04:13Now, pregnancy rate depends on the age of the female.
04:1730 to 39 years old, we are looking at 40 to 50% pregnancy rate.
04:22But overall, if you see, it's 30 to 40.
04:25In a good lab, in a good center, we're looking at 40 to 50%.
04:28Between 30 to 39 years old of the female partner, it will drop.
04:33At 40 years old, we drop to 20, 27% and drop much, much faster.
04:39Statistically, more than 45, your pregnancy rate would be less than 1%.
04:44Okay?
04:45So that's something that we need to always tell the patient.
04:48Some of the myths, if they do IVF, it's 100%.
04:51It's not.
04:52Right?
04:53So age then comes into the medicine.
04:55Sometimes you go, doctor's trying to push me for IVF.
04:57No, we're looking at your age.
04:59Right?
04:59We know this is the things that we experience statistically and also on a day-to-day basis.
05:05We do struggle when the wife's age is much more older.
05:10We do struggle when the wife makes her a child.
05:15We belong here.
05:17We're willing to finish the kitchen.
05:21I love you.
05:21I love you.
05:22I love you.
05:23I love you.

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