Xiao Yan swept the Yunlanzong and succeeded in revenge, but Yao Lao's soul was taken away by the Soul Palace. In order to catch Xiao Yan, the Soul Palace secretly borrowed the help of the little fairy doctor and ordered the Poison Sect to encircle and suppress Xiao Yan's Yan League. Although Xiao Yan, who had just been promoted to Douhuang, successfully resolved the crisis, he was also plagued by demonic poison spots. In order to get rid of the poison, and even more to understand the old medicine, Xiao Yan took the little doctor and Ziyan to Zhongzhou, but he didn't know that what was waiting for their fate was...
