Marvel's Spider-Man 2 is the first game in the series that allows players to play both Peter Parker (OG Senior Spidey) and Miles Morales (Junior Spidey). The game starts with Sandman (A.K.A. Flint Marko), trying to destroy the city.
As a new teacher, Parker finds it hard to juggle between his job as Spidey as well as responsible for his students well-being. Morales, on the other hand, as a student also had to keep his identity as the new Spidey unknown to many and yet it puts the school at danger. The scene will also be introducing a new main Villian, Kraven The Hunter.