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Naked Mole Rats Dig Carbon Dioxide
Live Science
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3/23/2025
We expel carbon dioxide as waste. Naked mole rats bathe their brains in it to prevent seizures. The unique animals thrive underground but cannot handle the lack of carbon dioxide above.
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Tech
Transcript
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00:00
Naked mole rats were already pretty strange, but now scientists have discovered a quirk
00:06
in their brains that makes them even weirder.
00:12
Naked mole rats live in underground colonies and must huddle together to keep warm, because
00:16
the rodents are essentially cold-blooded, meaning that their body temperature varies
00:21
drastically with their environment, rather than being regulated internally, like ours
00:25
is.
00:26
All cooped up underground, naked mole rats survive on very little oxygen and a ton of
00:31
carbon dioxide, which is expelled from the body as a waste product.
00:36
But now a study has revealed that naked mole rats actually need carbon dioxide to survive.
00:41
The compound tamps down their brain activity and keeps them from having seizures.
00:47
Researchers found that naked mole rats actually seek out areas of their nests with the highest
00:51
concentration of carbon dioxide.
00:54
But why?
00:55
Turns out, due to a genetic mutation, naked mole rats lack a control mechanism in their
01:01
brains that helps to keep its electrical activity under control.
01:05
This control mechanism uses up a lot of energy to run, so by relying on carbon dioxide instead,
01:12
the mole rats actually conserve precious energy stores.
01:16
When the human brain is exposed to carbon dioxide, its electrical activity can also
01:20
be suppressed.
01:22
This is a great hack for mole rats to use underground, but it leaves the rodents prone
01:27
to seizures if CO2 levels in their nests dip too low, or if they venture out into the air
01:33
outside their nests for some reason.
01:36
Some humans actually have the same genetic quirk that makes naked mole rats seizure-prone,
01:42
and these peoples appear to be at higher risk of certain forms of epilepsy.
01:47
For that reason, scientists think that naked mole rats might serve as a good animal model
01:53
to study certain types of seizures in people.
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