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Medico Macha
  • 6/21/2025
Transcript
00:00So, my dear friend, the next poison is spinal cord poison, which acts on the spinal cord.
00:05Now, how would you remember, sir?
00:07As for spinal cord, as for the poison name is strychnine.
00:13Strychnine.
00:15That is strikenes.
00:16Strykenes nuxvomica.
00:19Strykenes nuxvomica.
00:22Friend, this strychnine is also known as, the strikenes nuxvomica is also known as kuchila.
00:30It is known as kuchila, first word.
00:33Or it is also known as nuxvomica.
00:37It is also known as nuxvomica.
00:41And it is also used to kill stray dogs.
00:45It is also used for killing the stray dogs.
00:48That's why it is known as dog buttons.
00:52Dog buttons.
00:54Now, sir, if you see the seed shape, this question is very, very important, my dear friend.
01:00The shape of the seed is concavo-convex.
01:06The shape of a seed is concavo-convex for strychnine or strikenes nuxvomica, spinal cord.
01:13If you see, there is no order.
01:15It is orderless.
01:16But, my dear friend, the taste of the seed are bitter taste.
01:22Bitter taste of the seed.
01:24And the question comes regarding the fetal dose.
01:27Remember, sir, in fetal dose, the fetal dose is one, remember, one crushed seed.
01:34The fetal dose is one crushed seed.
01:39If it is uncrushed, it is not making any effect on the body.
01:43Fetal dose is one crushed seed.
01:47One crushed seed.
01:48Now, as you can see, these are strychnine seed, which are known as dog buttons.
01:54As I told you, these are known as dog button.
01:56Why it is known as dog button?
01:57To kill the stray dogs.
01:58If you see the shape, it is concavo-convex.
02:02Concavo-convex.
02:03And, dog, sir, by the name, by the name of strychnine, we can remember the name of the test also.
02:08Strychnine.
02:10Strychnine.
02:11Nene.
02:11The last is N.
02:12The test used for strychnine is vengel test.
02:18Vengel.
02:19Dog, sir, vengel has N.
02:21So, it's a vengel test.
02:22Because there is one more test, that's a vengel test for carbon monoxide poisoning.
02:26And, as for, you can remember, sonischine test.
02:33So, two tests are used.
02:35S for this one and N for vengel.
02:38Again, I'm telling you, wet gel.
02:42Wet gel test, it is used for carbon monoxide poisoning.
02:48So, in wet gel, we have T.
02:50In vengel, we have N.
02:52So, N for, it's a vengel test, is used for strychnine poisoning.
02:55And, sonischine test.
02:56These are two tests.
02:58Now, sir, what are the active principles?
02:59What are the important active principles seen in strychnine?
03:03The number one is strychnine itself.
03:09And, number two is brucine.
03:12Number one is strychnine itself.
03:15Number two is brucine.
03:16Both are alkaloid.
03:19Alkaloid.
03:20The third you can get in exam, that is loganine.
03:24And, my dear friend, loganine has G.
03:27It's a glucoside.
03:30It is glucoside.
03:32Look, sir.
03:32If you get a question, which is the most potent out of these?
03:36This is a very potential MCQ.
03:38Which active principle is the most potent out of these?
03:42The answer will be strychnine.
03:43It is almost 10 to 20 times more potent than brucine.
03:47Now, as I told you, it acts on the spinal cord.
03:50Two questions comes in exam.
03:51Where does it act?
03:53Sir, it acts in the anterior horn cell of the spinal cord.
04:00And, these cells are known as Ranshaw cells.
04:06These cells are known as Ranshaw cells.
04:09It acts on the spinal cord, anterior horn cell, Ranshaw cells.
04:12Now, sir, what it does?
04:14It completely blocks ventral motor neuron.
04:18And, postganglionic receptor site.
04:26It completely blocks postganglionic receptor site.
04:32And, also, after blocking this very, very important chemical mediator that is known as glycine.
04:40So, it inhibits or prevents the effect of glycine.
04:44Glycine is an inhibitory neurotransmitter.
04:47So, it inhibits the glycine.
04:49Overall effect will be excitatory.
04:53Overall effect will be excitatory.
04:55So, three question, anterior horn cell, postganglionic receptor site.
04:59And, it inhibits the glycine.
05:01Overall effect will be excitatory.
05:03So, if overall effect is excitatory, that is the reason it mimics a disease.
05:10This disease is tetanus.
05:13And, my dear friend, you have two phases.
05:16You have two phases.
05:17The one is, the one is convulsion phase.
05:21Another is relaxation phase.
05:22One is convulsion phase.
05:25Another is relaxation phase.
05:27Generally, what happens?
05:28Your relaxation phase duration is more.
05:33That is a normal situation.
05:36After any muscle, you have the convulsion relaxation.
05:39Conversion relaxation.
05:39But, sir, what happens in strychnine?
05:42Because it is excitatory, your convulsion duration, your convulsion duration increases.
05:50Your convulsion duration increases.
05:52So, there will be simultaneously few convulsions.
05:54Five to six convulsions.
05:57Five to six convulsions simultaneously.
05:59So, what will happen?
06:01There will be respiratory muscle spasm.
06:09The cause of death is respiratory muscle spasm.
06:13You won't be able to respirate.
06:14That will lead asphyxia.
06:17That will lead asphyxia.
06:19Very, very potential concept.
06:21So, there will be convulsion.
06:23Conversion duration is increased.
06:25Respiratory muscle spasm.
06:26That will lead asphyxia.
06:27Now, sir, in between all these convulsions, your consciousness is normal.
06:32That is retained.
06:34Your consciousness is retained.
06:37Okay?
06:37That's a very, very important part.
06:38But, sir, how to differentiate it from tetanus?
06:42How to differentiate?
06:43Because it makes tetanus.
06:44Difference is, in convulsion of this strychnine, muscles are affected.
06:49All the muscles are affected at the same time.
06:54All the muscles are affected at the same time.
06:56In tetanus, what happens?
06:58There is a sequential muscle involvement.
07:04Sequential muscle involvement.
07:06So, again, I am revising, my dear friend.
07:08In strychnine, all the muscles are affected at the same time.
07:12And when you give the external stimuli, very, very important, the intensity increases.
07:18When you give the external stimuli, the intensity increases.
07:24Intensity increases.
07:26Very, very potential.
07:27But, sir, you should avoid all type of external stimuli because it increases the intensity of convulsion.
07:33It is a convulsion.
07:35And it's a clonic convulsion.
07:37It is clonic convulsion.
07:41This is a very, very important one.
07:42Intensity increases if there is external stimuli.
07:45Now, sir, you have four, in fact, four important features.
07:50Three are tonus.
07:53Three are tonus and one is spasm.
07:56What are these three tonus positions, my dear friend?
07:58The first is ophistotonus.
08:02First is ophistotonus.
08:04Second is amprostotonus.
08:08Second is amprostotonus.
08:13And third is pleurostotonus.
08:18Ophistotonus, amprostotonus, pleurostotonus.
08:20What is ophistotonus?
08:22Ophistotonus is hyperextension.
08:24Ophistotonus is hyperextension of the back.
08:33Hyperextension of the back.
08:34What is amprostotonus?
08:36It is hyperflexion of this body.
08:41Hyperflexion.
08:42Ophistotonus, hyperextension of the back.
08:44And amprostotonus, hyperflexion of the back.
08:47And pleurostotonus is lateral bending.
08:50Pleurostotonus is lateral bending.
08:57Amprostotonus, and you can get a question.
08:59The most common is ophistotonus.
09:01Most common or most characteristic is ophistotonus.
09:04Now, spasm of the facial muscle.
09:08Spasm of the facial muscles.
09:10This condition is known as
09:12Rhysus sardonicus.
09:17This condition is known as
09:19Rhysus sardonicus.
09:21Spasm of facial muscles.
09:23This one.
09:23This is Rhysus sardonicus.
09:25Grimacing face.
09:26So, these are the common tonus and spasm condition
09:29is seen in strychnine.
09:30Very, very important.
09:31Sir, I already told you the test.
09:32And how to remember?
09:33I told you Vengel test.
09:37Very, very important.
09:38Vengel test.
09:39And the second is Soneshine test.
09:41I already discussed.
09:43Now, I am coming to a very, very important part.
09:45Treatment of strychnine poisoning.
09:48Treatment.
09:49Friend, as far as treatment is concerned,
09:52just try to avoid the gastric lavash
09:54because there are convulsions.
09:56So, try to avoid gastric lavash.
10:02Because of the situation,
10:05it precipitates convulsions.
10:07So, in convulsions,
10:08there is a relative contraindication
10:09of the gastric lavash.
10:10Now, control the seizure.
10:13First condition.
10:15First and the foremost,
10:16control the seizure.
10:18Second, sir,
10:20please stay away from stimuli
10:22because stimuli,
10:23by external stimuli,
10:25the intensity of the convulsions increases.
10:27So, no stimuli should be there.
10:29The person should be in the dark room,
10:32away from all the stimuli,
10:33away from the light.
10:34This is required.
10:35No stimuli should be there.
10:37Okay.
10:38Now, acidification of urine is done.
10:45Acidification of urine is done.
10:47For controlling the seizure,
10:49this question comes in exam.
10:51For controlling the seizure,
10:52we use phenobarbitone.
10:59Phenobarbitone.
11:01And we can use digepam.
11:06Digepam.
11:07So, this is the antidote.
11:08We use phenobarbitone.
11:09That can be used
11:10and digepam can be used.
11:12This is the treatment method.
11:14Now,
11:14post-martem findings.
11:16Sir,
11:16I already told you
11:17in the post-martem changes,
11:20in strickenene,
11:21the rigor mortis.
11:21What is RM?
11:22RM is rigor mortis.
11:24Rigor mortis comes early.
11:26That is early onset.
11:28But,
11:28my dear friend,
11:30it is of long duration.
11:33It is of long duration.
11:35And even in the post-martem changes,
11:37I told you the trick.
11:38ST,
11:38strickenene.
11:40E,
11:40early,
11:41steel,
11:42L,
11:42long duration.
11:42Early onset and long duration.
11:45Post-martem caloricity
11:46seen in strickenene poisoning,
11:49my dear friend.
11:49Generally,
11:50the temperature decreases.
11:51But in strickenene poisoning,
11:52the temperature increases
11:53after death for 1 to 2 hours.
11:55This is known as post-martem caloricity
11:56because of increased muscle activity.
11:59Putrefaction.
12:01The rate of putrefaction
12:02is decreased,
12:03my dear friend.
12:05Rate of putrefaction
12:06is decreased.
12:07I told you the trick.
12:08That was SMC.
12:10Strickenene,
12:11metallic poison,
12:12and carbon monoxide,
12:14carbolic acid,
12:14and cyanide poison.
12:16I told you the trick.
12:16That is putrefaction.
12:17The rate of putrefaction
12:18is decreased.
12:19And preserve.
12:21For strickenene poisoning,
12:22what you need to preserve?
12:23You need to preserve
12:24the brain
12:27and the foremost
12:28and the most important
12:30spinal cord.
12:31Very,
12:32very important
12:32spinal cord.
12:34Now,
12:34sir,
12:34this was an excitatory
12:36poison,
12:36strickenene.
12:37Now,
12:38one spinal poison
12:39which is
12:40galsamium,
12:41it is a inhibitory
12:43spinal cord poison.
12:47It is a inhibitory
12:49spinal cord poison.
12:50So,
12:51these are some
12:51very,
12:51very important
12:52spinal cord poison.
12:54The next
12:54very important
12:55category of the poison
12:56is cardiac poison.
12:57And you can remember
12:58by a trick
12:59queen donna.
13:01Queen donna.
13:02What is queen donna?
13:03The first
13:04is digitalis.
13:07The second
13:08is
13:09oleander.
13:11The first
13:12is digitalis.
13:13The second
13:14is oleander.
13:16That can be
13:17a white
13:18or pink
13:21oleander.
13:23Pink oleander
13:24or that can be
13:25a yellow
13:26oleander.
13:27The third
13:28is
13:29nicotina
13:30tabacum.
13:36Nicotina
13:36tabacum.
13:37And the
13:38fourth
13:38very,
13:39very important
13:39is
13:40echinite.
13:42And
13:43the
13:43fifth
13:44is
13:44quinine.
13:46Fifth
13:46is
13:47quinine.
13:48Very,
13:48very important.
13:49These are
13:50the example
13:51of cardiac
13:52poison.
13:52And if
13:52you want
13:52to add
13:53one more,
13:54you can
13:54add C
13:55for cardiac
13:56poison,
13:56C for
13:57cerebra
13:59odellum.
14:03Cerebra
14:03odellum.
14:05Cerebra
14:05odellum
14:06is another
14:06important cardiac
14:07poison.
14:08Okay,
14:09these are the
14:09category of
14:10the cardiac
14:10poison.
14:11Now,
14:11first,
14:12I am coming
14:12to echinite.
14:14Sir,
14:15echinite is
14:15also known
14:16as blue
14:17rocket.
14:19Another
14:19name is
14:20monk's
14:22hood.
14:24Blue
14:25rocket,
14:25you can
14:25see the
14:26floor.
14:26It's a
14:27blue.
14:27It is a
14:27blue
14:27rocket.
14:28Monk
14:28hood.
14:29And one
14:30very,
14:30very important
14:31word.
14:31It is
14:32also known
14:33as
14:34Mitha
14:34Jahar.
14:36All are
14:37the same.
14:37Echinite,
14:38monk hood,
14:39blue
14:39rocket,
14:40or
14:40Mitha
14:41Jahar.
14:42This
14:42question is
14:43very,
14:43very important.
14:44Sir,
14:44these are
14:45the roots
14:46of
14:46echinite.
14:48These,
14:49you can
14:49see the
14:49conical
14:50shape.
14:51Yes,
14:51my dear
14:51friend.
14:53Conical
14:53shape,
14:54tapered at
14:55the end,
14:56tapered at
14:58the end
14:58with
14:59longitudinal
15:00ridges.
15:01With
15:02longitudinal
15:02ridges,
15:03these are
15:03known as
15:04echinite
15:04root.
15:05The most
15:05poisonous
15:06substance is
15:07echinite
15:07root.
15:08Echinite.
15:10Now,
15:10sir,
15:11echinite is
15:11also known
15:12as
15:12monk hood,
15:13Mitha
15:14Jahar,
15:14or blue
15:14rocket.
15:15Friends,
15:16few questions
15:16have been
15:17asked.
15:18All the
15:19variety and
15:19all the
15:20parts of
15:21the plants
15:21are poisonous.
15:23All the
15:24variety and
15:24all the
15:24parts are
15:25poisonous.
15:26Most potent
15:27are root
15:28and seeds.
15:31It can
15:33cause
15:33accidental
15:33poisoning,
15:34my dear
15:34friend,
15:35because
15:35root are
15:36mistaken
15:37as
15:38horse
15:43reddish
15:45root.
15:46Root are
15:47mistaken
15:47as
15:48horse
15:48reddish
15:48root.
15:49That's
15:49accidental
15:50poisoning.
15:50That's
15:50why it
15:51is
15:51caused
15:51by
15:51active
15:52principle.
15:53Active
15:54principle
15:55are
15:55echinitine
15:57pseudo
15:59echinitine
16:01and
16:02echinitine.
16:04These
16:04all are
16:05important
16:05active
16:06principle.
16:06Echinitine,
16:07pseudo
16:08echinitine
16:08and
16:09echinitine.
16:10Very
16:10important.
16:12Now
16:12what is
16:13the
16:13mechanism
16:13of
16:14action?
16:14I
16:14just
16:15tell
16:15you
16:15some
16:15tricks
16:16which
16:16are
16:16very
16:16simple.
16:17Echinite
16:17has
16:18N
16:18so
16:19it
16:19mainly
16:20acts
16:20on
16:20sodium
16:21channel.
16:22Sodium
16:23channel.
16:24So
16:24what
16:24it
16:24causes?
16:25It
16:26causes
16:26actually
16:27it
16:27causes
16:28prolongation
16:29of
16:31sodium
16:33voltage
16:35channel.
16:37It
16:38causes
16:38prolongation
16:39of
16:39sodium
16:40voltage
16:40gated
16:41channel.
16:42Means
16:42prolong
16:42activation.
16:43Prolong
16:44activation.
16:45Very
16:45very
16:45important.
16:47Very
16:48very
16:48important.
16:48So
16:49what
16:49happens
16:49sir?
16:50It
16:50binds
16:50with
16:50the
16:51voltage
16:51gated
16:52sodium
16:53channel
16:54and
16:54it
16:54causes
16:55a
16:55prolonged
16:55activation
16:56of
16:56the
16:56sodium
16:56channel.
16:57Now
16:57because
16:58of
16:58this
16:59there
16:59will
16:59be
16:59stimulation
17:00of
17:00the
17:00sensory
17:01nerve.
17:01Remember
17:02sensory
17:03nerves
17:04are
17:04more
17:05commonly
17:06involved
17:06than
17:06motor
17:07nerve.
17:08Sensory
17:09involvement
17:09is more
17:10common
17:11than
17:11motor
17:11nerve.
17:12The
17:12motor
17:12ganglion
17:13of the
17:13heart
17:13are
17:14paralyzed.
17:14Definitely
17:15that
17:15will
17:15cause
17:15the
17:15heavy
17:15block
17:16and
17:16other
17:16situation.
17:18And
17:18respiratory
17:18sensory
17:19slow.
17:19Three
17:20things.
17:20Sensory
17:21nerve
17:21respiratory
17:23center.
17:24And
17:24this
17:24is
17:24very
17:25important
17:25that
17:25motor
17:26ganglion
17:26of
17:26the
17:27heart
17:27is
17:27getting
17:27paralyzed.
17:28These
17:28are
17:28three
17:29very
17:29important
17:29words.
17:30Prolonged
17:31activation
17:32of
17:32sodium
17:32voltage
17:33gated
17:33channel.
17:34That's
17:34a
17:34one
17:34one.
17:35Echo
17:35night
17:35night.
17:36Now
17:36what will
17:37be
17:37there?
17:38It
17:38will
17:38be
17:38tachy
17:39arrhythmia
17:39or
17:40tachycardia.
17:43Tachy
17:44arrhythmia
17:44or
17:44tachy
17:45cardia
17:45followed
17:46by
17:46Brady
17:47arrhythmia
17:48or
17:48Brady
17:48cardia.
17:49Brady
17:49arrhythmia.
17:51And friends
17:52this question
17:52comes in
17:53exam.
17:53The
17:53cause of
17:54death
17:54is
17:55cardiac
17:55arrhythmia.
17:57The
17:58cause of
17:59death
17:59is
17:59cardiac
18:00arrhythmia
18:00that is
18:01ventricular
18:03arrhythmia.
18:07Ventricular
18:07arrhythmia.
18:08That's
18:08the cause
18:08of death.
18:09Most
18:09common
18:10electrolytic
18:11problem
18:11that can
18:11come in
18:12aconite
18:12poisoning
18:13that is
18:13hyperkalemia.
18:17Hyperkalemia.
18:18You can
18:18get this
18:18question also.
18:19the most
18:20common
18:20is
18:20hyperkalemia.
18:23Very
18:23very important
18:24sir.
18:24Okay.
18:25Friends
18:25aconite
18:26sign and
18:27symptoms.
18:27Sometime
18:28you can
18:28get a
18:28question
18:28what
18:29are
18:29the
18:30important
18:30sign
18:30and
18:30symptom
18:31of
18:31aconite
18:31poisoning.
18:32First
18:33is
18:33tingling
18:34tingling
18:37and
18:37numbness.
18:40Tingling
18:41and
18:41numbness.
18:42Tingling
18:43is just
18:43like a
18:44pricking
18:44sensation
18:45and
18:46numbness.
18:47the loss
18:48of
18:48sensation
18:48in a
18:49particular
18:49part.
18:49That's
18:49a numbness
18:50of
18:51mouth
18:51and
18:52throat.
18:52This is
18:52most
18:53characteristic
18:53of this
18:54cardiac
18:54poison.
18:55Tingling
18:56and numbness
18:57of mouth
18:57and throat.
18:58No
18:59order.
18:59But I
19:00already
19:00told you
19:01generally
19:02it gives
19:02sweet
19:03taste.
19:04That's
19:04why.
19:04It's
19:04known as
19:05metha
19:05jahar.
19:06Metha
19:06jahar.
19:08Now
19:08sir,
19:08same
19:09thing.
19:09Very
19:09simple.
19:10Same
19:10thing.
19:11Numbness
19:12and
19:16prestesia.
19:21Numbness
19:22and
19:22prestesia.
19:23Numbness
19:23is a
19:24loss of
19:24sensation
19:24or a
19:25prestesia
19:25is an
19:25abnormal
19:26sensation.
19:27There
19:27may be
19:28a face
19:29perioral
19:30area
19:30then all
19:31over the
19:31body
19:32with
19:32weakness
19:33of the
19:33forelimbs.
19:34That
19:35means it
19:35starts from
19:35the area
19:36then it
19:36involves
19:36all
19:37forelimbs
19:37also.
19:39Very
19:39very
19:39important.
19:40Tweaching
19:40of the
19:41muscles.
19:42there
19:44will
19:45be
19:45twitching
19:45of
19:45the
19:46muscles.
19:47Then
19:47hippos
19:48sign.
19:49I'm
19:49expecting
19:49this
19:50question
19:50my
19:50dear
19:50friend.
19:51What
19:51is
19:52hippos
19:52sign?
19:53It
19:53is
19:53alternate
19:56contraction
19:59and
20:02dilation
20:03of
20:03pupil.
20:05It
20:05is
20:05alternate
20:06contraction
20:06and
20:07dilation
20:07of
20:07the
20:08pupil.
20:08This
20:09is
20:09known
20:09as
20:09hippos
20:10sign.
20:11Yes.
20:11Genthopsia.
20:12What
20:13is
20:13genthopsia?
20:14Yellow
20:15colored.
20:16Whenever
20:16gento
20:17word
20:17comes
20:18like
20:18gento
20:18protein
20:19reaction
20:19in
20:19nitric
20:19acid.
20:21So
20:21that
20:21is
20:21yellow.
20:22So
20:22yellow
20:23colored
20:23hello
20:23surrounding
20:26the
20:26object.
20:28Yellow
20:29colored
20:29hello
20:30surrounding
20:31the
20:31object.
20:31This
20:31is
20:32known
20:32as
20:32genthopsia.
20:33And
20:33definitely
20:34sir
20:34other
20:34feature
20:35which
20:35are
20:35other
20:36effect
20:36are
20:36hypotension,
20:37vedicardia,
20:39ventricular
20:39ectopics,
20:40cardiac
20:41arrhythmia and
20:42avi block.
20:44So
20:44these are
20:44common
20:45conditions
20:45seen in
20:46equonite
20:46poisoning.
20:47These
20:48are
20:48sequence
20:48of
20:49sequestion.
20:49Very
20:50very
20:50important
20:50equonite
20:51poisoning.
20:52Now
20:52sir
20:52what
20:52we
20:53do
20:53first
20:53just
20:54remember
20:54what
20:55is
20:55the
20:56root
20:56fatal
20:57dose.
20:58Sir
20:58very
20:59very
20:59important
20:591
21:00to
21:002
21:01gram
21:01of
21:01root
21:01is
21:01fatal
21:02for
21:02you.
21:031
21:03to
21:032
21:04gram
21:04is
21:04sufficient.
21:04Gastric
21:05lavage
21:06should
21:06be
21:06done
21:06with
21:07warm
21:07saline.
21:11Atropine
21:12is
21:12given
21:12for
21:13AV
21:14block.
21:16Atropine
21:17is
21:17given
21:17for
21:17AV
21:18block.
21:19Then
21:19supportive
21:19measures.
21:20Then
21:20you
21:20can
21:20write
21:21down
21:21supportive
21:21measures
21:22which
21:22is
21:22related
21:23for
21:23all
21:23important
21:24parameters.
21:28Supportive
21:29measures.
21:30So
21:30this
21:30is
21:30the
21:31treatment
21:31protocol
21:31for
21:32equonite.
21:33The
21:33most
21:33common
21:34electrolyte
21:34disturbance
21:34is
21:35hyperkalemia.
21:36Root
21:36fatal
21:36dose
21:37is
21:371
21:37to
21:372
21:37gram.
21:38Now
21:38sir
21:38what
21:38is
21:39the
21:39medical
21:39legal
21:39importance
21:40sir?
21:40As
21:40I
21:40told
21:41you
21:41it
21:41can
21:42cause
21:42accidental
21:42poisoning.
21:43How
21:43it
21:43can
21:43cause
21:44you
21:44can
21:44you
21:44can
21:44mistaken
21:45it
21:45as
21:45a
21:46horse
21:46reddish
21:47root.
21:48First
21:48second
21:49one
21:50of
21:50the
21:50ideal
21:51homicidal
21:53poison
21:54one
21:57of
21:57the
21:57ideal
21:57homicidal
21:58poison
21:58the
21:59reason
21:59is
22:00the
22:00fatal
22:00dose
22:01is
22:01very
22:01less
22:011
22:01to
22:012
22:02gram
22:02and
22:03it
22:03mimics
22:04the
22:05natural
22:05cardiac
22:06arrhythmia.
22:06It
22:07mimics
22:07cardiac
22:08arrhythmia.
22:10Cardiac
22:11arrhythmia.
22:15That's
22:15why
22:16it
22:16can
22:16be
22:17used
22:17as
22:17a
22:17homicidal
22:18poison.
22:19And
22:19sir
22:19this
22:20is
22:20destroyed
22:21by
22:21putrefaction.
22:23It
22:23means
22:23sir
22:23after
22:24some
22:24time
22:25it
22:25is
22:25destroyed
22:25by
22:25the
22:25putrefaction
22:26so
22:27you
22:27cannot
22:27detect
22:28a
22:28conite
22:28in
22:29your
22:29body.
22:29That's
22:30why
22:30it's
22:30commonly
22:30used
22:30as
22:30a
22:31homicidal
22:31poison.
22:32This
22:32is
22:33econite.
22:34Mithajahar
22:34blue
22:35rocket
22:35or
22:35monk
22:36hood.
22:37A
22:37pus
22:37sign
22:37you
22:37can
22:38get
22:38a
22:38question.
22:39Treatment
22:39you
22:39can
22:39get
22:40a
22:40question.
22:40Name
22:41you
22:41can
22:41get
22:41a
22:41question.
22:42The
22:42picture
22:42of
22:43blue
22:44rocket
22:44you
22:44can
22:44get
22:44a
22:45question.
22:45This
22:45is
22:45first
22:46cardiac
22:46poison
22:46that
22:47is
22:47econite.
22:48Now
22:48I
22:48am
22:48coming
22:49to
22:49another
22:49cardiac
22:50poison
22:50that
22:50is
22:51yellow
22:51oleander.
22:53Friends
22:53yellow
22:54oleander
22:55as
22:55the name
22:55suggests
22:56it
22:57is
22:57also
22:58known
22:58as
22:58pila
22:59kaneer.
23:03Peela
23:03kaneer.
23:05Peela
23:05kaneer.
23:07Yellow
23:07oleander
23:08is also
23:08known
23:08as
23:09pila
23:09kaneer.
23:10The
23:10important
23:12name
23:13which
23:13we
23:13use
23:13for
23:14yellow
23:15oleander
23:15is
23:16cerebra
23:16thivacea.
23:19Cerebra
23:19thivacea.
23:21So
23:21the
23:21active
23:22principle
23:22are
23:22without
23:23any
23:23doubt
23:24the
23:24active
23:24principle
23:25are
23:25number
23:26one
23:26cerebrine
23:27cerebrine
23:29thivotoxin
23:30it can
23:32be of
23:32two
23:32type
23:32thivotoxin
23:33a
23:33and
23:34thivotoxin
23:34b
23:35and
23:36nerifolene
23:38nerifolene
23:42these
23:42all
23:42are
23:43the
23:43active
23:43principle
23:43of
23:44yellow
23:44oleander
23:45pila
23:45kaneer
23:46or
23:46cerebra
23:46thivacea
23:47and
23:47remember
23:48sir
23:48all
23:49part
23:49are
23:52poisonous
23:53all
23:56part
23:56are
23:57poisonous
23:57of
23:58this
23:58yellow
23:58oleander
23:59or
23:59cerebra
23:59thivacea
24:00you can
24:00see
24:01the
24:01yellow
24:02flower
24:02that's
24:03a
24:03yellow
24:04oleander
24:04or
24:04cerebra
24:05thivacea
24:05now
24:06sir
24:07pink
24:07oleander
24:08pink
24:09very very
24:10important
24:10sir
24:10how would
24:10you remember
24:11sir
24:11pink
24:11pink has
24:13a word
24:13n
24:13and
24:14pink has
24:15a word
24:15k
24:16it is
24:17known
24:17as
24:17kaneer
24:18that is
24:20pink
24:20kaneer
24:21or
24:21white
24:22oleander
24:22that's
24:23a
24:23saped
24:24kaneer
24:25so
24:25normally
24:26it is
24:26pink
24:26color
24:27or
24:27it can
24:27be
24:28white
24:28also
24:28kaneer
24:29n
24:30n
24:32for
24:32it is
24:33also
24:33known
24:34as
24:34the
24:34botanical
24:34name
24:35is
24:35nerium
24:36odorum
24:37nerium
24:38odorum
24:39very very
24:40important
24:40it is
24:41nerium
24:41odorum
24:42these are
24:42some
24:43very very
24:43important
24:43k
24:44kaneer
24:44n
24:45nerium
24:45odorum
24:46it's
24:46a
24:46pinky
24:46pinkish
24:47white
24:48oleander
24:48we can
24:49use a
24:49word
24:49sometime
24:50it is
24:50white
24:51oleander
24:51also
24:52it is
24:52a
24:52pink
24:52oleander
24:52now
24:53what are
24:53the
24:54active
24:54principle
24:54see
24:55it's
24:56very
24:56simple
24:56it is
24:57nerine
24:58yes
24:59my
24:59different
24:59it is
25:00nerine
25:00nerium
25:00odorum
25:01it's
25:01a
25:01nerine
25:01it is
25:03foley
25:03nerine
25:04it is
25:05foley
25:06nerine
25:06foley
25:08nerine
25:08it is
25:09oleandrine
25:10it is
25:12oleandrine
25:13this is
25:14known as
25:15nerium
25:15odorum
25:16and if you
25:17want to go
25:17in detail
25:18rosa
25:19janine
25:20another
25:22rosa
25:22looking like
25:23a rose
25:23rosa
25:24janine
25:25these all
25:26are active
25:26principle
25:26nerine
25:27foley
25:28nerine
25:28rosa
25:29janine
25:29and oleandrine
25:30these all
25:31are the
25:31active
25:31principle
25:32of
25:32pinky
25:33pink
25:34nk
25:34nerium
25:35odorum
25:35kaneer
25:36which is
25:36known as
25:37pink
25:37kaneer
25:37or
25:38saped
25:38kaneer
25:39kaneer
25:39vade
25:40jesus
25:40the mechanism
25:41of these
25:42two plant
25:42if you want
25:43to go
25:43in detail
25:44the mechanism
25:45of these
25:46two plant
25:47it is
25:48similar to
25:49digitalis
25:50digitalis
25:52everyone knows
25:52digitalis
25:53is a
25:54cardiac
25:54glycoside
25:55it is
25:56similar to
25:56this
25:57digitalis
25:57it inhibits
25:58sodium
26:00potassium
26:02atypase
26:04channel
26:05sodium
26:06potassium
26:07atypase
26:08channel
26:09it inhibits
26:09sodium
26:10potassium
26:10atypase
26:10channel
26:11my dear
26:13friend
26:13it causes
26:14bradycardia
26:15and tachycardia
26:16bradycardia
26:18and tachycardia
26:18it causes
26:19heavy block
26:20and it
26:22causes
26:22hyperkalemia
26:23hyperkalemia
26:24now if you
26:25see the
26:26treatment
26:26part
26:27my dear
26:27friend
26:27it is
26:28gastric
26:29lavase
26:29first we
26:31go for
26:31gastric
26:31lavase
26:32with warm
26:33saline
26:34and these
26:34gastric
26:35lavase
26:35will go
26:35now sir
26:36antidote
26:37look sir
26:37this is a
26:38very important
26:38antidote
26:39for oleander
26:39is digibind
26:40and even
26:42the antidote
26:43for digitalis
26:44is also
26:45digibind
26:46what is the
26:48function of
26:49the digibind
26:49it binds
26:51to
26:52a fabi
26:54portion
26:54of
26:56antibody
26:57it binds
26:59it binds
26:59to
27:00fab
27:01portion
27:01of
27:02antibody
27:03now
27:03for
27:04for
27:05av block
27:06without
27:07any doubt
27:07we give
27:08atropine
27:08yes my
27:11dear friend
27:11for correcting
27:13hyperkalemia
27:14we give
27:14dextrose
27:15and
27:18insulin
27:18so these
27:21are some
27:22very very
27:22important
27:23treatment
27:23modality
27:24for this
27:25one
27:25that is
27:25oleander
27:26both
27:28oleander
27:28that is
27:29yellow
27:29oleander
27:29pila
27:30canir
27:30and
27:31pink
27:32oleander
27:32that is
27:33known as
27:33canir
27:33that is
27:34known as
27:34canir
27:35now the
27:35next
27:36very very
27:36important
27:37cardiac
27:37poison
27:37is
27:37digitalis
27:38digitalis
27:39purpura
27:39friends
27:40it is
27:41also known
27:42as
27:42purple
27:43fox
27:46glow
27:47it is
27:48known as
27:49a purple
27:49fox
27:50glow
27:50and I
27:51already
27:51discussed
27:51the
27:52mechanism
27:52it
27:53inhibits
27:54the
27:54channel
27:54which
27:55is
27:55sodium
27:57potassium
27:58atypase
28:00sodium
28:02potassium
28:03atypase
28:03the same
28:04mechanism
28:04of action
28:05of oleander
28:05plant
28:06so same
28:07treatment
28:08protocol
28:09will be
28:09there for
28:10digitalis
28:11purpura
28:12same treatment
28:14protocol
28:14same
28:14gastric
28:15lavase
28:15will go
28:15for
28:16digibind
28:16will go
28:17for
28:17atropine
28:17will go
28:18for
28:18drugs
28:19for
28:20tachycardia
28:20will go
28:21for
28:21tachyredmia
28:21and without
28:23any doubt
28:24for correcting
28:25hyperkalemia
28:26dextrose
28:26and insulin
28:27are given
28:27so same
28:28treatment
28:28protocol
28:28it's a
28:29purple
28:29fox
28:30glow
28:30you can
28:31see
28:31because
28:31this
28:31question
28:32or this
28:32image
28:32can come
28:33in your
28:33exam
28:33cerebroodolum
28:36my dear
28:37friend
28:37cerebroodolum
28:39is also
28:40known as
28:41suicidal
28:41tree
28:42suicidal
28:45tree
28:45my dear
28:47friend
28:48what are
28:48the active
28:49principle
28:49cerebrine
28:50cerebrine
28:52cerebrocide
28:57from
28:58cerebra
28:58odoline
29:03and
29:06odolotoxin
29:07these are
29:09the active
29:10principle of
29:10cerebraodolum
29:11and you can
29:12get one
29:12question sir
29:13we use a
29:15specific regime
29:16for cerebra
29:18odolum
29:19that is known
29:19as bist
29:20regime
29:20this is
29:21known as
29:21bist
29:22regime
29:23very very
29:24potential MCQ
29:24it is known
29:25as bist
29:26regime
29:26for cerebra
29:27odolum
29:28and of
29:29some I
29:29told you
29:29nicotina
29:30tobacum
29:31so you
29:31just remember
29:32one more
29:32important word
29:33nicotine
29:35or tobacco
29:37is the
29:40most common
29:41substance
29:43use
29:47and
29:49abuse
29:51in India
29:52most common
29:54substance
29:54use and
29:56abuse in
29:57India
29:57is tobacco
29:57it is tobacco
29:59but not
30:00illicit
30:00if you got a
30:01question
30:01most common
30:02illicit
30:03illicit is
30:05illegal
30:05which is not
30:06legal in
30:06India
30:06the answer
30:07will be
30:08cannabis
30:09most common
30:11illicit
30:11substance
30:12use and
30:13abuse in
30:14India
30:14that will
30:15be cannabis
30:15so if
30:16illicit word
30:17comes the
30:17answer become
30:18cannabis
30:18otherwise
30:19it is
30:20tobacco
30:20tobacco
30:21tambaku
30:22so these
30:23are some
30:23very very
30:24important
30:25cardiac
30:26poison
30:26these are
30:27some
30:27very very
30:28important
30:28cardiac
30:29poison
30:29so if
30:30you
30:31have
30:31to
30:32have
30:32to
30:33have
30:33you
30:34have
30:34to
30:35have
30:35you
30:36have
30:36to
30:36have