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Report
The Ozempic shortage, explained
Brut America
Follow
2/1/2023
Ozempic, a groundbreaking medication for the treatment of Type 2 diabetes, has been in shortage in recent months. But are those using the drug for weight loss really to blame? Brut investigated ...
Category
🛠️
Lifestyle
Transcript
Display full video transcript
00:00
Everyone is on Ozempic.
00:01
It's a miracle.
00:02
It's too good to be true.
00:03
You might have heard of Ozempic, a type 2 diabetes medication that also happens to be
00:07
really effective for weight loss.
00:10
Celebrities rumored to have used Ozempic have been accused of sparking a social media frenzy
00:13
around the drug, causing a shortage.
00:16
People are doing Ozempic parties here in LA, where they all do Ozempic.
00:20
But the reasons for the shortage are a lot more nuanced.
00:23
Let's take a look at how we got here.
00:29
Ozempic was developed by pharmaceutical company Novo Nordisk and FDA approved in 2017.
00:35
It was a game changer for people with type 2 diabetes looking to lower their blood sugar.
00:42
People with type 2 diabetes are excited about the potential of once weekly Ozempic.
00:47
Since it helps the body to make more insulin, the insulin helps to lower the glucose.
00:51
Also since it slows down how quickly food moves from your stomach to your intestines,
00:55
your blood sugars don't spike as much after you eat.
00:57
So it gives your body more time to match those carbohydrates.
01:01
In clinical trials, researchers found that Ozempic was really effective for weight loss.
01:05
So Novo Nordisk rebranded semaglutide as Wigovi for weight loss at a bit of a higher dose
01:10
than Ozempic.
01:11
The active ingredient in Ozempic and Wigovi is identical.
01:14
It's the same medication, it's semaglutide.
01:17
To me, it's ridiculous that they need to make two different medications that are exactly
01:20
the same and label them differently.
01:22
But nonetheless.
01:23
In 2021, Wigovi was FDA approved for people with obesity or overweight with at least one
01:29
weight-related condition.
01:30
Do they have sleep apnea, type 2 diabetes, high blood pressure, high cholesterol, polycystic
01:36
ovarian syndrome?
01:37
Because those are all things that if the obesity is treated, will also secondarily be treated.
01:44
In trials, Wigovi helped people lose on average nearly 15% of their starting body weight.
01:49
The drug was a godsend for people who had struggled to lose weight and managed their
01:53
weight-related conditions even after changing their diet and exercise.
01:57
When Wigovi was launched, the company really went out and marketed it well.
02:04
Plus they had this savings card so that people could get it at a relatively inexpensive rate.
02:09
It being once a week, people were more willing to do it.
02:14
And the weight loss that we saw was substantially higher than with the other medications.
02:20
Wigovi became so popular that Novo Nordisk couldn't keep up with the demand, but doctors
02:24
were told the shortage was temporary.
02:27
And so many physicians thought, well, if it's temporary, then we'll prescribe Ozempic instead
02:32
to tide them over until the Wigovi problem is fixed.
02:35
But the problem then was the Wigovi shortage kept going on.
02:39
And then there was the Ozempic shortage.
02:42
Doctors were able to prescribe Ozempic off-label for weight loss, which is permitted once the
02:46
treatment is cleared for something other than type 2 diabetes.
02:50
And unlike Wigovi, it's easier to get covered by insurance, encouraging more doctors to prescribe it.
02:55
Wigovi, on the other hand, is a lot harder to get covered because there are some plans
03:00
that just have a blanket, we don't cover weight loss medications, they won't cover anything.
03:03
Word of Ozempic spread among celebrities who could afford to buy it without coverage, and
03:08
several public figures have commented on its use in Hollywood.
03:11
Everyone is on Ozempic.
03:13
It's a miracle.
03:14
It's too good to be true.
03:15
I didn't even know I was on it.
03:16
I stopped taking it.
03:17
That's too irresponsible.
03:21
Ozempic then started trending on TikTok, where hashtag Ozempic stands at over 470 million
03:28
views as of the time of this recording.
03:31
So I'm starting Ozempic today.
03:35
Week 17 Ozempic update.
03:37
What I ate for lunch as a midsize girl on Ozempic.
03:40
In the past, when I was trying to prescribe weight loss medications to people, they'd be
03:43
very hesitant.
03:45
Once they saw that famous people were doing it and it was OK and it was cool, more people
03:51
wanted it.
03:53
So at this point, Ozempic is being prescribed for both diabetes and weight loss.
03:57
And as news of the shortages came out, many accused people using the drug for weight loss
04:02
of taking away crucial medicine from people with type 2 diabetes.
04:06
Thanks to the hashtag Ozempic journey, there is a shortage of Ozempic.
04:12
I can't get the Ozempic that I need and that my body responds to well because a bunch of
04:18
people decided, oh, well, I'm just going to use it to lose weight.
04:22
But those using off-label Ozempic for weight loss say obesity is also a chronic illness
04:27
and that the vast majority of these prescriptions are written for people with obesity or overweight
04:31
with at least one weight related condition.
04:34
Yes, I'm primarily using it for weight loss.
04:37
However, there were underlying issues that I was having due to my weight.
04:43
I was almost 250 pounds and I lost 105 pounds from this medicine.
04:50
I'm no longer pre-diabetic.
04:52
My high blood pressure is gone.
04:55
I'm not being selfish by any means by using this medication.
05:00
I'm trying to be here longer for my children.
05:04
I think that there are people who truly need the medication to improve their health who,
05:09
in an act of desperation, because they couldn't get the drug they're supposed to get, which
05:14
is the Wegovy, got Ozempic.
05:17
The people who are using it because they just want to be pretty.
05:20
I don't agree with that part.
05:22
But I think that's a minority of the people who are using it because those people can't
05:26
get it through insurance.
05:27
They're not going to be able to get it approved.
05:28
So these are just people with a whole lot of money to throw at something that's cosmetic.
05:33
For people who use semaglutide for weight loss, stopping or switching medications can
05:37
worsen any weight-related conditions.
05:39
Obesity is a chronic illness and needs to be treated like a chronic illness, just like
05:44
we treat high blood pressure.
05:45
You don't give someone a high blood pressure pill and say, oh, your blood pressure is normal
05:48
now, we can stop it.
05:49
So what happens if someone with type 2 diabetes can't get access to their Ozempic prescription?
05:54
Well, they could switch to a different medication, but they'd be missing out on benefits only
05:59
Ozempic can provide.
06:01
It's been shown to decrease the risk of cardiovascular events, and not all diabetes medications have
06:07
been shown to do that.
06:08
And for people who have fatty liver, there's also data that it's helpful for that.
06:11
So how did we get here?
06:13
Well, if you combine the groundbreaking effectiveness of semaglutide for both diabetes treatment
06:18
and weight loss, Novo Nordisk's hardcore marketing of these drugs, celebrity rumors, the power
06:24
of TikTok and manufacturing delays, we get the shortages we have today.
06:28
I can understand why people who are doing well on their Ozempic feel angry that they
06:35
can't get it now because people are using it for other purposes.
06:40
But I don't blame the people who are using it.
06:44
I blame the lack of manufacturing.
06:47
We live in a country where over two thirds of the population is over, are either overweight
06:52
or obese.
06:53
We live in a country where over 25 million people have diabetes, most of whom have type
06:57
2.
06:58
If you're going to say we want you to use our drug all the time, then you better be
07:05
prepared to give all these people medication.
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