Treatment For Male/Female Baldness

The key to curing male hair loss may come from the unlikeliest source: an ugly hairy mole. Stem cell researchers at UC-Irvine have discovered that such moles contain hair stem cell hyperactivity. Investigating the triggers for hair growth in these moles using a mouse model, they found overproduction of a hair signaling factor called osteopontin or SPP1 by aging pigment cells in these hairy moles. Osteopontin binds to an antigen on the surface of hair follicle cells and stimulates their production of new hair. Still under study are the factors that drive aging cells to produce the hair-promoting osteopontin. When that is better understood, it may be possible to prevent hair loss in men, and in some women, as they age. We hope that understand comes……someday soon.

https://www.nature.com/articles/s41586-023-06172-8

#baldness #moles #hairmoles #aging #osteopontin #ssp1